The last time the New Madrid Seismic Zone had a major series of earthquakes along it was in the year 1811 and 1812. The biggest, on 12/16/1812 was the largest recorded earthquake in the United States. This estimated magnitude 8.3 earthquake kicked major league butt among the native american and settler populations that inhabited the midwest during that time. If it were to happen today a large number of very large cities that have never experienced an earthquake before would be hit by a monster.
Well, the monster is moving again.